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Widespread reorganisation of pluripotent factor binding and gene regulatory interactions between human pluripotent states
The transition from naive to primed pluripotency is accompanied by an extensive reorganisation of transcriptional and epigenetic programmes. However, the role of transcriptional enhancers and three-dimensional chromatin organisation in coordinating these developmental programmes remains incompletely...
Autores principales: | Chovanec, Peter, Collier, Amanda J., Krueger, Christel, Várnai, Csilla, Semprich, Claudia I., Schoenfelder, Stefan, Corcoran, Anne E., Rugg-Gunn, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026613/ https://www.ncbi.nlm.nih.gov/pubmed/33828098 http://dx.doi.org/10.1038/s41467-021-22201-4 |
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