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Placebo response mitigation with a participant-focused psychoeducational procedure: a randomized, single-blind, all placebo study in major depressive and psychotic disorders
The remarkably high and growing placebo response rates in clinical trials for CNS indications, such as depression and schizophrenia, constitute a major challenge for the drug development enterprise. Despite extensive literature on participant expectancies and other potent psychosocial factors that p...
Autores principales: | Cohen, Elan A., Hassman, Howard H., Ereshefsky, Larry, Walling, David P., Grindell, Vera M., Keefe, Richard S. E., Wyka, Katarzyna, Horan, William P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026614/ https://www.ncbi.nlm.nih.gov/pubmed/33244149 http://dx.doi.org/10.1038/s41386-020-00911-5 |
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