Cargando…
Pyruvate dehydrogenase kinases (PDKs): an overview toward clinical applications
Pyruvate dehydrogenase kinase (PDK) can regulate the catalytic activity of pyruvate decarboxylation oxidation via the mitochondrial pyruvate dehydrogenase complex, and it further links glycolysis with the tricarboxylic acid cycle and ATP generation. This review seeks to elucidate the regulation of P...
Autores principales: | Wang, Xiuxiu, Shen, Xiaoyue, Yan, Yuting, Li, Hongmin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026821/ https://www.ncbi.nlm.nih.gov/pubmed/33739396 http://dx.doi.org/10.1042/BSR20204402 |
Ejemplares similares
-
Targeting Tumor Metabolism for Cancer Treatment: Is Pyruvate Dehydrogenase Kinases (PDKs) a Viable Anticancer Target?
por: Zhang, Wen, et al.
Publicado: (2015) -
Differential inhibition of PDKs by phenylbutyrate and enhancement of pyruvate dehydrogenase complex activity by combination with dichloroacetate
por: Ferriero, Rosa, et al.
Publicado: (2015) -
Transcriptional Regulation of Pyruvate Dehydrogenase Kinase
por: Jeong, Ji Yun, et al.
Publicado: (2012) -
The Role of Pyruvate Dehydrogenase Kinase in Diabetes and Obesity
por: Lee, In-Kyu
Publicado: (2014) -
The pivotal role of pyruvate dehydrogenase kinases in metabolic flexibility
por: Zhang, Shuai, et al.
Publicado: (2014)