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Iguratimod promotes transformation of mononuclear macrophages in elderly patients with rheumatoid arthritis by nuclear factor-κB pathway

BACKGROUND: The role of macrophages in rheumatoid arthritis (RA) and its mechanism have attracted much attention in RA pathogenesis. Macrophages accumulate in the synoviums of RA, and the proportion of M1 type pro-inflammatory macrophages is higher than that of M2 type anti-inflammatory macrophages,...

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Detalles Bibliográficos
Autores principales: Liu, Sha, Song, Li-Ping, Li, Rong-Bin, Feng, Le-Heng, Zhu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026846/
https://www.ncbi.nlm.nih.gov/pubmed/33869594
http://dx.doi.org/10.12998/wjcc.v9.i10.2181