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Consistency of the S5 DNA methylation classifier in formalin‐fixed biopsies versus corresponding exfoliated cells for the detection of pre‐cancerous cervical lesions

Methylation biomarkers are promising tools for diagnosis and disease prevention. The S5 classifier is aimed at the prevention of cervical cancer by the early detection of cervical intraepithelial neoplasia (CIN). S5 is based on pyrosequencing a promoter region of EPB41L3 and five late regions of HPV...

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Detalles Bibliográficos
Autores principales: Reuter, Caroline, Preece, Matthew, Banwait, Rawinder, Boer, Sabrina, Cuzick, Jack, Lorincz, Attila, Nedjai, Belinda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026949/
https://www.ncbi.nlm.nih.gov/pubmed/33710792
http://dx.doi.org/10.1002/cam4.3849