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Beyond DNA repair and chromosome instability—Fanconi anaemia as a cellular senescence-associated syndrome
Fanconi anaemia (FA) is the most frequent inherited bone marrow failure syndrome, due to mutations in genes encoding proteins involved in replication fork protection, DNA interstrand crosslink repair and replication rescue through inducing double-strand break repair and homologous recombination. Cli...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026967/ https://www.ncbi.nlm.nih.gov/pubmed/33723374 http://dx.doi.org/10.1038/s41418-021-00764-5 |