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Beyond DNA repair and chromosome instability—Fanconi anaemia as a cellular senescence-associated syndrome

Fanconi anaemia (FA) is the most frequent inherited bone marrow failure syndrome, due to mutations in genes encoding proteins involved in replication fork protection, DNA interstrand crosslink repair and replication rescue through inducing double-strand break repair and homologous recombination. Cli...

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Detalles Bibliográficos
Autores principales: Helbling-Leclerc, Anne, Garcin, Cécile, Rosselli, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026967/
https://www.ncbi.nlm.nih.gov/pubmed/33723374
http://dx.doi.org/10.1038/s41418-021-00764-5