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Efficient IL-2R signaling differentially affects the stability, function, and composition of the regulatory T-cell pool

Signaling via interleukin-2 receptor (IL-2R) is a requisite for regulatory T (Treg) cell identity and function. However, it is not completely understood to what degree IL-2R signaling is required for Treg cell homeostasis, lineage stability and function in both resting and inflammatory conditions. H...

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Detalles Bibliográficos
Autores principales:	Permanyer, Marc, Bošnjak, Berislav, Glage, Silke, Friedrichsen, Michaela, Floess, Stefan, Huehn, Jochen, Patzer, Gwendolyn E., Odak, Ivan, Eckert, Nadine, Zargari, Razieh, Ospina-Quintero, Laura, Georgiev, Hristo, Förster, Reinhold
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027001/ https://www.ncbi.nlm.nih.gov/pubmed/33408345 http://dx.doi.org/10.1038/s41423-020-00599-z

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