Cargando…
Perturbations of cancer cell metabolism by the antidiabetic drug canagliflozin
Notwithstanding that high rates of glucose uptake and glycolysis are common in neoplasia, pharmacological efforts to inhibit glucose utilization for cancer treatment have not been successful. Recent evidence suggests that in addition to classical glucose transporters, sodium-glucose transporters (SG...
Autores principales: | Papadopoli, David, Uchenunu, Oro, Palia, Ranveer, Chekkal, Nabila, Hulea, Laura, Topisirovic, Ivan, Pollak, Michael, St-Pierre, Julie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027095/ https://www.ncbi.nlm.nih.gov/pubmed/33784591 http://dx.doi.org/10.1016/j.neo.2021.02.003 |
Ejemplares similares
-
Oncogenic kinases and perturbations in protein synthesis machinery and energetics in neoplasia
por: Uchenunu, Oro, et al.
Publicado: (2018) -
Mitochondrial complex IV defects induce metabolic and signaling perturbations that expose potential vulnerabilities in HCT116 cells
por: Uchenunu, Oro, et al.
Publicado: (2022) -
mTOR as a central regulator of lifespan and aging
por: Papadopoli, David, et al.
Publicado: (2019) -
mTOR coordinates protein synthesis, mitochondrial activity and proliferation
por: Morita, Masahiro, et al.
Publicado: (2015) -
The mitochondrial pyruvate carrier complex potentiates the efficacy of proteasome inhibitors in multiple myeloma
por: Findlay, Steven, et al.
Publicado: (2023)