Leaky Gut Driven by Dysbiosis Augments Activation and Accumulation of Liver Macrophages via RIP3 Signaling Pathway in Autoimmune Hepatitis

The gut–liver axis has been increasingly recognized as a major autoimmunity modulator. However, the implications of intestinal barrier in the pathogenesis of autoimmune hepatitis (AIH) remain elusive. Here, we investigated the functional role of gut barrier and intestinal microbiota for hepatic inna...

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Detalles Bibliográficos
Autores principales: Zhang, Hongxia, Liu, Man, Zhong, Weilong, Zheng, Yanping, Li, Yanni, Guo, Liping, Zhang, Yujie, Ran, Ying, Zhao, Jingwen, Zhou, Lu, Wang, Bangmao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027109/
https://www.ncbi.nlm.nih.gov/pubmed/33841405
http://dx.doi.org/10.3389/fimmu.2021.624360

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