A novel CD4+ CTL subtype characterized by chemotaxis and inflammation is involved in the pathogenesis of Graves’ orbitopathy

Graves’ orbitopathy (GO), the most severe manifestation of Graves’ hyperthyroidism (GH), is an autoimmune-mediated inflammatory disorder, and treatments often exhibit a low efficacy. CD4+ T cells have been reported to play vital roles in GO progression. To explore the pathogenic CD4+ T cell types th...

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Detalles Bibliográficos
Autores principales: Wang, Yue, Chen, Ziyi, Wang, Tingjie, Guo, Hui, Liu, Yufeng, Dang, Ningxin, Hu, Shiqian, Wu, Liping, Zhang, Chengsheng, Ye, Kai, Shi, Bingyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027210/
https://www.ncbi.nlm.nih.gov/pubmed/33514849
http://dx.doi.org/10.1038/s41423-020-00615-2

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