C-Reactive Protein Suppresses the Th17 Response Indirectly by Attenuating the Antigen Presentation Ability of Monocyte Derived Dendritic Cells in Experimental Autoimmune Encephalomyelitis

Experimental autoimmune encephalomyelitis (EAE) is a classical murine model for Multiple Sclerosis (MS), a human autoimmune disease characterized by Th1 and Th17 responses. Numerous studies have reported that C-reactive protein (CRP) mitigates EAE severity, but studies on the relevant pathologic mec...

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Detalles Bibliográficos
Autores principales: Shen, Zhi-Yuan, Zheng, Yi, Pecsok, Maggie K., Wang, Ke, Li, Wei, Gong, Min-Jie, Wu, Feng, Zhang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027258/
https://www.ncbi.nlm.nih.gov/pubmed/33841391
http://dx.doi.org/10.3389/fimmu.2021.589200

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