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Multiple antisense oligonucleotides targeted against monoacylglycerol acyltransferase 1 (Mogat1) improve glucose metabolism independently of Mogat1

OBJECTIVE: Monoacylglycerol acyltransferase (MGAT) enzymes catalyze the synthesis of diacylglycerol from monoacylglycerol. Previous work has suggested the importance of MGAT activity in the development of obesity-related hepatic insulin resistance. Indeed, antisense oligonucleotide (ASO)-mediated kn...

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Detalles Bibliográficos
Autores principales:	Lutkewitte, Andrew J., Singer, Jason M., Shew, Trevor M., Martino, Michael R., Hall, Angela M., He, Mai, Finck, Brian N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027266/ https://www.ncbi.nlm.nih.gov/pubmed/33676028 http://dx.doi.org/10.1016/j.molmet.2021.101204

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