Cargando…

ARHGEF18/p114RhoGEF Coordinates PKA/CREB Signaling and Actomyosin Remodeling to Promote Trophoblast Cell-Cell Fusion During Placenta Morphogenesis

Coordination of cell-cell adhesion, actomyosin dynamics and gene expression is crucial for morphogenetic processes underlying tissue and organ development. Rho GTPases are main regulators of the cytoskeleton and adhesion. They are activated by guanine nucleotide exchange factors in a spatially and t...

Descripción completa

Detalles Bibliográficos
Autores principales: Beal, Robert, Alonso-Carriazo Fernandez, Ana, Grammatopoulos, Dimitris K., Matter, Karl, Balda, Maria S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027320/
https://www.ncbi.nlm.nih.gov/pubmed/33842485
http://dx.doi.org/10.3389/fcell.2021.658006