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ARHGEF18/p114RhoGEF Coordinates PKA/CREB Signaling and Actomyosin Remodeling to Promote Trophoblast Cell-Cell Fusion During Placenta Morphogenesis
Coordination of cell-cell adhesion, actomyosin dynamics and gene expression is crucial for morphogenetic processes underlying tissue and organ development. Rho GTPases are main regulators of the cytoskeleton and adhesion. They are activated by guanine nucleotide exchange factors in a spatially and t...
Autores principales: | Beal, Robert, Alonso-Carriazo Fernandez, Ana, Grammatopoulos, Dimitris K., Matter, Karl, Balda, Maria S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027320/ https://www.ncbi.nlm.nih.gov/pubmed/33842485 http://dx.doi.org/10.3389/fcell.2021.658006 |
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