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Regulation of the SIAH2-HIF-1 Axis by Protein Kinases and Its Implication in Cancer Therapy
The cellular response to hypoxia is a key biological process that facilitates adaptation of cells to oxygen deprivation (hypoxia). This process is critical for cancer cells to adapt to the hypoxic tumor microenvironment resulting from rapid tumor growth. Hypoxia-inducible factor 1 (HIF-1) is a trans...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027324/ https://www.ncbi.nlm.nih.gov/pubmed/33842469 http://dx.doi.org/10.3389/fcell.2021.646687 |