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Toll-like receptor 7 deficiency suppresses type 1 diabetes development by modulating B-cell differentiation and function

Innate immunity mediated by Toll-like receptors (TLRs), which can recognize pathogen molecular patterns, plays a critical role in type 1 diabetes development. TLR7 is a pattern recognition receptor that senses single-stranded RNAs from viruses and host tissue cells; however, its role in type 1 diabe...

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Detalles Bibliográficos
Autores principales:	Huang, Juan, Peng, Jian, Pearson, James Alexander, Efthimiou, Georgios, Hu, Youjia, Tai, Ningwen, Xing, Yanpeng, Zhang, Luyao, Gu, Jianlei, Jiang, Jianping, Zhao, Hongyu, Zhou, Zhiguang, Wong, F. Susan, Wen, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027372/ https://www.ncbi.nlm.nih.gov/pubmed/33432061 http://dx.doi.org/10.1038/s41423-020-00590-8

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