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Heart failure—emerging roles for the mitochondrial pyruvate carrier

The mitochondrial pyruvate carrier (MPC) is the entry point for the glycolytic end-product pyruvate to the mitochondria. MPC activity, which is controlled by its abundance and post-translational regulation, determines whether pyruvate is oxidised in the mitochondria or metabolised in the cytosol. MP...

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Detalles Bibliográficos
Autores principales: Fernandez-Caggiano, Mariana, Eaton, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027425/
https://www.ncbi.nlm.nih.gov/pubmed/33473180
http://dx.doi.org/10.1038/s41418-020-00729-0