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Serum Zonulin Measured by Commercial Kit Fails to Correlate With Physiologic Measures of Altered Gut Permeability in First Degree Relatives of Crohn's Disease Patients

Intestinal epithelial cell tight junctions (TJs) contribute to the integrity of the intestinal barrier allowing for control of the physical barrier between external antigens or bacterial products and the internal environment. Zonula occludens-1 (ZO-1) is a protein that modulates intestinal TJs, and...

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Detalles Bibliográficos
Autores principales: Power, Namita, Turpin, Williams, Espin-Garcia, Osvaldo, Smith, Michelle I., Croitoru, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027468/
https://www.ncbi.nlm.nih.gov/pubmed/33841181
http://dx.doi.org/10.3389/fphys.2021.645303