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Streptococcal protein SIC activates monocytes and induces inflammation

Streptococcus pyogenes is a major bacterial pathogen in the human population and isolates of the clinically important M1 serotype secrete protein Streptococcal inhibitor of complement (SIC) known to interfere with human innate immunity. Here we find that SIC from M1 bacteria interacts with TLR2 and...

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Detalles Bibliográficos
Autores principales:	Neumann, Ariane, Happonen, Lotta, Karlsson, Christofer, Bahnan, Wael, Frick, Inga-Maria, Björck, Lars
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027542/ https://www.ncbi.nlm.nih.gov/pubmed/33855284 http://dx.doi.org/10.1016/j.isci.2021.102339

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