A novel luminescence-based β-arrestin recruitment assay for unmodified receptors

G protein-coupled receptors (GPCRs) signal through activation of G proteins and subsequent modulation of downstream effectors. More recently, signaling mediated by β-arrestin has also been implicated in important physiological functions. This has led to great interest in the identification of biased...

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Detalles Bibliográficos
Autores principales: Hauge Pedersen, Maria, Pham, Jennifer, Mancebo, Helena, Inoue, Asuka, Asher, Wesley B., Javitch, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027564/
https://www.ncbi.nlm.nih.gov/pubmed/33684444
http://dx.doi.org/10.1016/j.jbc.2021.100503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027564/
https://www.ncbi.nlm.nih.gov/pubmed/33684444
http://dx.doi.org/10.1016/j.jbc.2021.100503

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