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Effect of selection bias on two sample summary data based Mendelian randomization

Mendelian randomization (MR) is becoming more and more popular for inferring causal relationship between an exposure and a trait. Typically, instrument SNPs are selected from an exposure GWAS based on their summary statistics and the same summary statistics on the selected SNPs are used for subseque...

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Detalles Bibliográficos
Autores principales: Wang, Kai, Han, Shizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027662/
https://www.ncbi.nlm.nih.gov/pubmed/33828182
http://dx.doi.org/10.1038/s41598-021-87219-6

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