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Effect of selection bias on two sample summary data based Mendelian randomization
Mendelian randomization (MR) is becoming more and more popular for inferring causal relationship between an exposure and a trait. Typically, instrument SNPs are selected from an exposure GWAS based on their summary statistics and the same summary statistics on the selected SNPs are used for subseque...
Autores principales: | Wang, Kai, Han, Shizhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027662/ https://www.ncbi.nlm.nih.gov/pubmed/33828182 http://dx.doi.org/10.1038/s41598-021-87219-6 |
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