Cargando…

YAP–TEAD1 control of cytoskeleton dynamics and intracellular tension guides human pluripotent stem cell mesoderm specification

The tight regulation of cytoskeleton dynamics is required for a number of cellular processes, including migration, division and differentiation. YAP–TEAD respond to cell–cell interaction and to substrate mechanics and, among their downstream effects, prompt focal adhesion (FA) gene transcription, th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pagliari, Stefania, Vinarsky, Vladimir, Martino, Fabiana, Perestrelo, Ana Rubina, Oliver De La Cruz, Jorge, Caluori, Guido, Vrbsky, Jan, Mozetic, Pamela, Pompeiano, Antonio, Zancla, Andrea, Ranjani, Sri Ganji, Skladal, Petr, Kytyr, Dan, Zdráhal, Zbyněk, Grassi, Gabriele, Sampaolesi, Maurilio, Rainer, Alberto, Forte, Giancarlo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027678/ https://www.ncbi.nlm.nih.gov/pubmed/33116297 http://dx.doi.org/10.1038/s41418-020-00643-5

Ejemplares similares

Cellular Mechanotransduction: From Tension to Function
por: Martino, Fabiana, et al.
Publicado: (2018)

YAP regulates cell mechanics by controlling focal adhesion assembly
por: Nardone, Giorgia, et al.
Publicado: (2017)

Generation and maturation of human iPSC-derived 3D organotypic cardiac microtissues in long-term culture
por: Ergir, Ece, et al.
Publicado: (2022)

A primer to traction force microscopy
por: Zancla, Andrea, et al.
Publicado: (2022)

Gatekeepers of pancreas: TEAD and YAP
por: Rodríguez-Seguí, Santiago A., et al.
Publicado: (2015)

Valproic acid stimulates myogenesis in pluripotent stem cell-derived mesodermal progenitors in a NOTCH-dependent manner
por: Breuls, Natacha, et al.
Publicado: (2021)

Functional Analysis of Dishevelled-3 Phosphorylation Identifies Distinct Mechanisms Driven by Casein Kinase 1ϵ and Frizzled5
por: Bernatík, Ondřej, et al.
Publicado: (2014)

Repurposing of Drugs Targeting YAP-TEAD Functions
por: Elisi, Gian Marco, et al.
Publicado: (2018)

MicroRNAs promote skeletal muscle differentiation of mesodermal iPSC-derived progenitors
por: Giacomazzi, Giorgia, et al.
Publicado: (2017)

Advanced and Rationalized Atomic Force Microscopy Analysis Unveils Specific Properties of Controlled Cell Mechanics
por: Caluori, Guido, et al.
Publicado: (2018)

KIF14 controls ciliogenesis via regulation of Aurora A and is important for Hedgehog signaling
por: Pejskova, Petra, et al.
Publicado: (2020)

Crystal structure of TAZ-TEAD complex reveals a distinct interaction mode from that of YAP-TEAD complex
por: Kaan, Hung Yi Kristal, et al.
Publicado: (2017)

Time-dependent Pax3-mediated chromatin remodeling and cooperation with Six4 and Tead2 specify the skeletal myogenic lineage in developing mesoderm
por: Magli, Alessandro, et al.
Publicado: (2019)

Elicitin-Induced Distal Systemic Resistance in Plants is Mediated Through the Protein–Protein Interactions Influenced by Selected Lysine Residues
por: Uhlíková, Hana, et al.
Publicado: (2016)

Identification of Celastrol as a Novel YAP-TEAD Inhibitor for Cancer Therapy by High Throughput Screening with Ultrasensitive YAP/TAZ–TEAD Biosensors
por: Nouri, Kazem, et al.
Publicado: (2019)

VGLL3 operates via TEAD1, TEAD3 and TEAD4 to influence myogenesis in skeletal muscle
por: Figeac, Nicolas, et al.
Publicado: (2019)

Toward the Discovery of a Novel Class of YAP–TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAP–TEAD Protein–Protein Interface
por: Gibault, Floriane, et al.
Publicado: (2018)

Multifaceted function of YAP/TEAD on chromatin:prospects of ‘A non-canonical role of YAP/TEAD is required for activation of estrogen-regulated enhancers in breast cancer’
por: Chen, Lizhen, et al.
Publicado: (2019)

A combat with the YAP/TAZ-TEAD oncoproteins for cancer therapy
por: Pobbati, Ajaybabu V., et al.
Publicado: (2020)

A complex role of Arabidopsis CDKD;3 in meiotic progression and cytokinesis
por: Tanasa, Sorin, et al.
Publicado: (2023)

TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors
por: Cebola, Inês, et al.
Publicado: (2015)

Retinal Degeneration Triggers the Activation of YAP/TEAD in Reactive Müller Cells
por: Hamon, Annaïg, et al.
Publicado: (2017)

FLNC Expression Level Influences the Activity of TEAD-YAP/TAZ Signaling
por: Knyazeva, Anastasia, et al.
Publicado: (2020)

Protein-Protein Interaction Disruptors of the YAP/TAZ-TEAD Transcriptional Complex
por: Pobbati, Ajaybabu V., et al.
Publicado: (2020)

Study of the TEAD‐binding domain of the YAP protein from animal species
por: Mesrouze, Yannick, et al.
Publicado: (2020)

The Hippo pathway in cancer: YAP/TAZ and TEAD as therapeutic targets in cancer
por: Cunningham, Richard, et al.
Publicado: (2022)

Wnt and Src signals converge on YAP‐TEAD to drive intestinal regeneration
por: Guillermin, Oriane, et al.
Publicado: (2021)

Covalent disruptor of YAP-TEAD association suppresses defective Hippo signaling
por: Fan, Mengyang, et al.
Publicado: (2022)

Microfluidic Organ/Body-on-a-Chip Devices at the Convergence of Biology and Microengineering
por: Perestrelo, Ana Rubina, et al.
Publicado: (2015)

TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells
por: Elster, Dana, et al.
Publicado: (2018)

Transformation of normal cells by aberrant activation of YAP via cMyc with TEAD
por: Nishimoto, Masazumi, et al.
Publicado: (2019)

Dissection of the interaction between the intrinsically disordered YAP protein and the transcription factor TEAD
por: Mesrouze, Yannick, et al.
Publicado: (2017)

Pharmacological blockade of TEAD–YAP reveals its therapeutic limitation in cancer cells
por: Sun, Yang, et al.
Publicado: (2022)

The lateral plate mesoderm
por: Prummel, Karin D., et al.
Publicado: (2020)

YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers
por: Stein, Claudia, et al.
Publicado: (2015)

YAP/TEAD Co-Activator Regulated Pluripotency and Chemoresistance in Ovarian Cancer Initiated Cells
por: Xia, Yan, et al.
Publicado: (2014)

Dropwort-induced metabolic reprogramming restrains YAP/TAZ/TEAD oncogenic axis in mesothelioma
por: Pulito, Claudio, et al.
Publicado: (2019)

Homeobox A4 suppresses vascular remodeling by repressing YAP/TEAD transcriptional activity
por: Kimura, Masahiro, et al.
Publicado: (2020)

YAP‐TEAD up‐regulates IRS2 expression to induce and deteriorate oesophageal cancer
por: Xu, Xiangming, et al.
Publicado: (2021)

Simplifying cancer: binary pan-cancer superclasses stratified by opposite YAP/TEAD effects
por: Pearson, Joel D., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_hq4827t2e89tbks7o2jrl1at65