NOX4 promotes ferroptosis of astrocytes by oxidative stress-induced lipid peroxidation via the impairment of mitochondrial metabolism in Alzheimer's diseases

Oxidative stress has been implicated in the pathogenesis of Alzheimer's disease (AD). Mitochondrial dysfunction is linked to oxidative stress and reactive oxygen species (ROS) in neurotoxicity during AD. Impaired mitochondrial metabolism has been associated with mitochondrial dysfunction in bra...

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Detalles Bibliográficos
Autores principales: Park, Min Woo, Cha, Hyeon Woo, Kim, Junhyung, Kim, Jung Han, Yang, Haesung, Yoon, Sunmi, Boonpraman, Napissara, Yi, Sun Shin, Yoo, Ik Dong, Moon, Jong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027773/
https://www.ncbi.nlm.nih.gov/pubmed/33774476
http://dx.doi.org/10.1016/j.redox.2021.101947

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