Cargando…

Decreased striatal adenosine A(2A)-dopamine D(2) receptor heteromerization in schizophrenia

According to the adenosine hypothesis of schizophrenia, the classically associated hyperdopaminergic state may be secondary to a loss of function of the adenosinergic system. Such a hypoadenosinergic state might either be due to a reduction of the extracellular levels of adenosine or alterations in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Valle-León, Marta, Callado, Luis F., Aso, Ester, Cajiao-Manrique, María M., Sahlholm, Kristoffer, López-Cano, Marc, Soler, Concepció, Altafaj, Xavier, Watanabe, Masahiko, Ferré, Sergi, Fernández-Dueñas, Víctor, Menchón, José M., Ciruela, Francisco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8027896/ https://www.ncbi.nlm.nih.gov/pubmed/33010795 http://dx.doi.org/10.1038/s41386-020-00872-9

Ejemplares similares

Adenosine A(2A)-dopamine D(2) receptor heteromers operate striatal function: impact on Parkinson's disease pharmacotherapeutics
por: Fernández-Dueñas, Víctor, et al.
Publicado: (2018)

Functional and Neuroprotective Role of Striatal Adenosine A(2A) Receptor Heterotetramers
por: Ferré, Sergi, et al.
Publicado: (2019)

Adenosine A(1)-A(2A) Receptor Heteromer as a Possible Target for Early-Onset Parkinson's Disease
por: Fernández-Dueñas, Víctor, et al.
Publicado: (2017)

Heteromerization of Dopamine D2 and Oxytocin Receptor in Adult Striatal Astrocytes
por: Amato, Sarah, et al.
Publicado: (2023)

Adenosine Receptor Heteromers and their Integrative Role in Striatal Function
por: Ferré, Sergi, et al.
Publicado: (2007)

Untangling dopamine-adenosine receptor-receptor assembly in experimental parkinsonism in rats
por: Fernández-Dueñas, Víctor, et al.
Publicado: (2015)

Overcoming the Challenges of Detecting GPCR Oligomerization in the Brain
por: Fernández-Dueñas, Víctor, et al.
Publicado: (2022)

Revealing Adenosine A(2A)-Dopamine D(2) Receptor Heteromers in Parkinson’s Disease Post-Mortem Brain through a New AlphaScreen-Based Assay
por: Fernández-Dueñas, Víctor, et al.
Publicado: (2019)

Voltage-Dependent Dopamine Potency at D(1)-Like Dopamine Receptors
por: Ågren, Richard, et al.
Publicado: (2020)

Pridopidine Reverses Phencyclidine-Induced Memory Impairment
por: Sahlholm, Kristoffer, et al.
Publicado: (2018)

Dopamine-induced arrestin recruitment and desensitization of the dopamine D4 receptor is regulated by G protein-coupled receptor kinase-2
por: Burström, Viktor, et al.
Publicado: (2023)

The Parkinson’s disease-associated GPR37 receptor interacts with striatal adenosine A(2A) receptor controlling its cell surface expression and function in vivo
por: Morató, Xavier, et al.
Publicado: (2017)

Brain Iron Deficiency Changes the Stoichiometry of Adenosine Receptor Subtypes in Cortico-Striatal Terminals: Implications for Restless Legs Syndrome
por: Rodrigues, Matilde S., et al.
Publicado: (2022)

Heteromerization of G-Protein–Coupled Receptors. Implications for Central Nervous System Function and Dysfunction
por: Ferré, Sergi
Publicado: (2007)

Clues from a missense mutation of the adenosine A(1) receptor gene associated with early-onset Parkinson’s disease
por: Ferré, Sergi, et al.
Publicado: (2023)

Significant Functional Differences Between Dopamine D(4) Receptor Polymorphic Variants Upon Heteromerization with α(1A) Adrenoreceptors
por: Homar-Ruano, Patricia, et al.
Publicado: (2023)

Circadian-Related Heteromerization of Adrenergic and Dopamine D(4) Receptors Modulates Melatonin Synthesis and Release in the Pineal Gland
por: González, Sergio, et al.
Publicado: (2012)

Uncovering Caffeine’s Adenosine A(2A) Receptor Inverse Agonism in Experimental Parkinsonism
por: Fernández-Dueñas, Víctor, et al.
Publicado: (2014)

Antipsychotics with similar association kinetics at dopamine D(2) receptors differ in extrapyramidal side-effects
por: Zeberg, Hugo, et al.
Publicado: (2018)

Optical Control of Adenosine-Mediated Pain Modulation
por: Hüll, Katharina, et al.
Publicado: (2021)

Evidence for Two Modes of Binding of the Negative Allosteric Modulator SB269,652 to the Dopamine D(2) Receptor
por: Ågren, Richard, et al.
Publicado: (2021)

Dopamine D3 Receptor Heteromerization: Implications for Neuroplasticity and Neuroprotection
por: Bono, Federica, et al.
Publicado: (2020)

Striatal Pre- and Postsynaptic Profile of Adenosine A(2A) Receptor Antagonists
por: Orru, Marco, et al.
Publicado: (2011)

Striatal Dopamine D(2)-Muscarinic Acetylcholine M(1) Receptor–Receptor Interaction in a Model of Movement Disorders
por: Crans, René A. J., et al.
Publicado: (2020)

Corrigendum: Striatal dopamine D2-muscarinic acetylcholine M1 receptor-receptor interaction in a model of movement disorders
por: Crans, René A. J., et al.
Publicado: (2022)

Allosteric Interactions between Adenosine A(2A) and Dopamine D(2) Receptors in Heteromeric Complexes: Biochemical and Pharmacological Characteristics, and Opportunities for PET Imaging
por: Prasad, Kavya, et al.
Publicado: (2021)

Key Modulatory Role of Presynaptic Adenosine A(2A) Receptors in Cortical Neurotransmission to the Striatal Direct Pathway
por: Quiroz, César, et al.
Publicado: (2009)

Adenosine A(2A) Receptors and A(2A) Receptor Heteromers as Key Players in Striatal Function
por: Ferré, Sergi, et al.
Publicado: (2011)

Adenosine A(2A) Receptors Are Upregulated in Peripheral Blood Mononuclear Cells from Atrial Fibrillation Patients
por: Godoy-Marín, Héctor, et al.
Publicado: (2021)

Dopaminergic-cholinergic imbalance in movement disorders: a role for the novel striatal dopamine D(2)- muscarinic acetylcholine M(1) receptor heteromer
por: Crans, René A. J., et al.
Publicado: (2020)

Dopamine D(2) Receptor Agonist Binding Kinetics—Role of a Conserved Serine Residue
por: Ågren, Richard, et al.
Publicado: (2021)

The Beta-Arrestin-Biased Dopamine D(2) Receptor Ligand, UNC9994, Is a Partial Agonist at G-Protein-Mediated Potassium Channel Activation
por: Ågren, Richard, et al.
Publicado: (2018)

Control of glutamate release by complexes of adenosine and cannabinoid receptors
por: Köfalvi, Attila, et al.
Publicado: (2020)

Membrane omega-3 fatty acids modulate the oligomerisation kinetics of adenosine A(2A) and dopamine D(2) receptors
por: Guixà-González, Ramon, et al.
Publicado: (2016)

PBF509, an Adenosine A(2A) Receptor Antagonist With Efficacy in Rodent Models of Movement Disorders
por: Núñez, Fabiana, et al.
Publicado: (2018)

Cortical Control of Striatal Dopamine Transmission via Striatal Cholinergic Interneurons
por: Kosillo, Polina, et al.
Publicado: (2016)

Local control of striatal dopamine release
por: Cachope, Roger, et al.
Publicado: (2014)

Abnormal Striatal Dopamine Transmission in Schizophrenia
por: Brunelin, Jerome, et al.
Publicado: (2013)

Striatal Dopamine Signals and Reward Learning
por: Bech, Pol, et al.
Publicado: (2023)

Ligand with Two Modes of Interaction with the Dopamine D(2) Receptor–An Induced-Fit Mechanism of Insurmountable Antagonism
por: Ågren, Richard, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7fikbaf1fb6cmi58kg4bnvjgvu