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Identification of PIK3CA multigene mutation patterns associated with superior prognosis in stomach cancer
BACKGROUND: PIK3CA is the second most frequently mutated gene in cancers and is extensively studied for its role in promoting cancer cell resistance to chemotherapy or targeted therapy. However, PIK3CA functions have mostly been investigated at a lower-order genetic level, and therapeutic strategies...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8028071/ https://www.ncbi.nlm.nih.gov/pubmed/33827485 http://dx.doi.org/10.1186/s12885-021-08115-w |