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Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation

The anaphase-promoting complex/cyclosome (APC/C) is an E3 ubiquitin ligase that controls cell cycle transitions. Its regulation by the spindle assembly checkpoint (SAC) is coordinated with the attachment of sister chromatids to the mitotic spindle. APC/C SUMOylation on APC4 ensures timely anaphase o...

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Detalles Bibliográficos
Autores principales:	Yatskevich, Stanislau, Kroonen, Jessie S., Alfieri, Claudio, Tischer, Thomas, Howes, Anna C., Clijsters, Linda, Yang, Jing, Zhang, Ziguo, Yan, Kaige, Vertegaal, Alfred C.O., Barford, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8028313/ https://www.ncbi.nlm.nih.gov/pubmed/33789095 http://dx.doi.org/10.1016/j.celrep.2021.108929

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