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Prostatic urethral lift (UroLift): a real-world analysis of outcomes using hospital episodes statistics

BACKGROUND: To determine real-world outcomes of prostatic urethral lift (UroLift) procedures conducted in hospitals across England. METHODS: A retrospective observational cohort was identified from Hospital Episode Statistics data including men undergoing UroLift in hospitals in England between 2017...

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Autores principales: Page, Toby, Veeratterapillay, Rajan, Keltie, Kim, Burn, Julie, Sims, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8028737/
https://www.ncbi.nlm.nih.gov/pubmed/33827525
http://dx.doi.org/10.1186/s12894-021-00824-5
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author Page, Toby
Veeratterapillay, Rajan
Keltie, Kim
Burn, Julie
Sims, Andrew
author_facet Page, Toby
Veeratterapillay, Rajan
Keltie, Kim
Burn, Julie
Sims, Andrew
author_sort Page, Toby
collection PubMed
description BACKGROUND: To determine real-world outcomes of prostatic urethral lift (UroLift) procedures conducted in hospitals across England. METHODS: A retrospective observational cohort was identified from Hospital Episode Statistics data including men undergoing UroLift in hospitals in England between 2017 and 2020. Procedure uptake, patient demographics, inpatient complications, 30-day accident and emergency re-attendance rate, requirement for further treatment and catheterization were captured. Kaplan–Meier and hazard analysis were used to analyse time to re-treatment. RESULTS: 2942 index UroLift procedures from 80 hospital trusts were analysed; 85.3% conducted as day-case surgery (admitted to hospital for a planned surgical procedure and returning home on the same day). In-hospital complication rate was 3.4%. 93% of men were catheter-free at 30 days. The acute accident and emergency attendance rate within 30 days was 12.0%. Results of Kaplan Meier analysis for subsequent re-treatment (including additional UroLift and endoscopic intervention) at 1 and 2 years were 5.2% [95% CI 4.2 to 6.1] and 11.9% [10.1 to 13.6] respectively. CONCLUSIONS: This real-world analysis of UroLift shows that it can be delivered safely in a day-case setting with minimal morbidity. However, hospital resource usage for catheterization and emergency hospital attendance in the first 30 days was substantial, and 12% required re-treatment at 2 years. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12894-021-00824-5.
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spelling pubmed-80287372021-04-08 Prostatic urethral lift (UroLift): a real-world analysis of outcomes using hospital episodes statistics Page, Toby Veeratterapillay, Rajan Keltie, Kim Burn, Julie Sims, Andrew BMC Urol Research Article BACKGROUND: To determine real-world outcomes of prostatic urethral lift (UroLift) procedures conducted in hospitals across England. METHODS: A retrospective observational cohort was identified from Hospital Episode Statistics data including men undergoing UroLift in hospitals in England between 2017 and 2020. Procedure uptake, patient demographics, inpatient complications, 30-day accident and emergency re-attendance rate, requirement for further treatment and catheterization were captured. Kaplan–Meier and hazard analysis were used to analyse time to re-treatment. RESULTS: 2942 index UroLift procedures from 80 hospital trusts were analysed; 85.3% conducted as day-case surgery (admitted to hospital for a planned surgical procedure and returning home on the same day). In-hospital complication rate was 3.4%. 93% of men were catheter-free at 30 days. The acute accident and emergency attendance rate within 30 days was 12.0%. Results of Kaplan Meier analysis for subsequent re-treatment (including additional UroLift and endoscopic intervention) at 1 and 2 years were 5.2% [95% CI 4.2 to 6.1] and 11.9% [10.1 to 13.6] respectively. CONCLUSIONS: This real-world analysis of UroLift shows that it can be delivered safely in a day-case setting with minimal morbidity. However, hospital resource usage for catheterization and emergency hospital attendance in the first 30 days was substantial, and 12% required re-treatment at 2 years. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12894-021-00824-5. BioMed Central 2021-04-07 /pmc/articles/PMC8028737/ /pubmed/33827525 http://dx.doi.org/10.1186/s12894-021-00824-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Page, Toby
Veeratterapillay, Rajan
Keltie, Kim
Burn, Julie
Sims, Andrew
Prostatic urethral lift (UroLift): a real-world analysis of outcomes using hospital episodes statistics
title Prostatic urethral lift (UroLift): a real-world analysis of outcomes using hospital episodes statistics
title_full Prostatic urethral lift (UroLift): a real-world analysis of outcomes using hospital episodes statistics
title_fullStr Prostatic urethral lift (UroLift): a real-world analysis of outcomes using hospital episodes statistics
title_full_unstemmed Prostatic urethral lift (UroLift): a real-world analysis of outcomes using hospital episodes statistics
title_short Prostatic urethral lift (UroLift): a real-world analysis of outcomes using hospital episodes statistics
title_sort prostatic urethral lift (urolift): a real-world analysis of outcomes using hospital episodes statistics
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8028737/
https://www.ncbi.nlm.nih.gov/pubmed/33827525
http://dx.doi.org/10.1186/s12894-021-00824-5
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