Cargando…

miR-155-5p upregulation ameliorates myocardial insulin resistance via mTOR signaling in chronic alcohol drinking rats

BACKGROUND: Chronic alcohol intake is associated with an increased risk of alcoholic cardiomyopathy, which may present with pathological changes such as myocardial insulin resistance, leading to ventricular dilation and cardiac dysfunction. Although a correlation between microRNA-155 (miR-155) and i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Zhaoping, Hu, Zhenzhen, Meng, Yan, Xu, Hongzhao, Wei, Yali, Shen, Deqiang, Bai, Hao, Yuan, Huacai, Chen, Liyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2021
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8029671/ https://www.ncbi.nlm.nih.gov/pubmed/33868799 http://dx.doi.org/10.7717/peerj.10920

Ejemplares similares

Involvement of TOB1 on autophagy in gastric cancer AGS cells via decreasing the activation of AKT/mTOR signaling pathway
por: Wang, Dong, et al.
Publicado: (2022)

Rasgrp1 mutation increases naïve T-cell CD44 expression and drives mTOR-dependent accumulation of Helios(+) T cells and autoantibodies
por: Daley, Stephen R, et al.
Publicado: (2013)

Sophocarpine inhibits tumor progression by antagonizing the PI3K/AKT/mTOR signaling pathway in castration-resistant prostate cancer
por: Weng, Min, et al.
Publicado: (2022)

Inhibition of Connexin 43 reverses ox-LDL-mediated inhibition of autophagy in VSMC by inhibiting the PI3K/Akt/mTOR signaling pathway
por: Qin, Xuqing, et al.
Publicado: (2022)

Melatonin ameliorates myocardial injury by reducing apoptosis and autophagy of cardiomyocytes in a rat cardiopulmonary bypass model
por: Huang, Xiaolin, et al.
Publicado: (2021)

Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace
por: Heimhalt, Maren, et al.
Publicado: (2021)

Four sesquiterpene glycosides from loquat (Eriobotrya japonica) leaf ameliorates palmitic acid-induced insulin resistance and lipid accumulation in HepG2 Cells via AMPK signaling pathway
por: Li, Jiawei, et al.
Publicado: (2020)

Cbl upregulates cysH for hydrogen sulfide production in Aeromonas veronii
por: Zhang, Yidong, et al.
Publicado: (2021)

Effects of Vitamin D Supplementation in Patients with Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis
por: Wei, Yali, et al.
Publicado: (2020)

Substrate specificity of TOR complex 2 is determined by a ubiquitin-fold domain of the Sin1 subunit
por: Tatebe, Hisashi, et al.
Publicado: (2017)

Myocardial contrast echocardiography assessment of mouse myocardial infarction: comparison of kinetic parameters with conventional methods
por: Thielen, Nicholas T., et al.
Publicado: (2021)

Microbial community spatial structures in Luzhou-flavored liquor pit muds with different brewing materials
por: Li, Jinjin, et al.
Publicado: (2022)

Bioinformatics prediction and experimental verification of a novel microRNA for myocardial fibrosis after myocardial infarction in rats
por: Guo, Qianqian, et al.
Publicado: (2023)

Oleanolic acid and moderate drinking increase the pancreatic GLP-1R expression of the β-cell mass deficiency induced hyperglycemia
por: Xu, Li, et al.
Publicado: (2023)

Low temperature upregulating HSP70 expression to mitigate the paclitaxel-induced damages in NHEK cell
por: Chen, Liang, et al.
Publicado: (2023)

Concentration-dependent polymorphism of insulin amyloid fibrils
por: Sakalauskas, Andrius, et al.
Publicado: (2019)

A model of multiple tumor marker for lymph node metastasis assessment in colorectal cancer: a retrospective study
por: Fu, Jiangping, et al.
Publicado: (2022)

Rutin ameliorates carbon tetrachloride (CCl(4))-induced hepatorenal toxicity and hypogonadism in male rats
por: Elsawy, Hany, et al.
Publicado: (2019)

Ameliorative effect of apelin-13 against renal complications in L-NAME-induced preeclampsia in rats
por: Hamza, Reham Z., et al.
Publicado: (2021)

Knockdown of CNN3 Impairs Myoblast Proliferation, Differentiation, and Protein Synthesis via the mTOR Pathway
por: She, Yanling, et al.
Publicado: (2021)

Ligand-binding characteristics of feline insulin-binding immunoglobulin G
por: SUZUKI, Takafumi, et al.
Publicado: (2015)

Exploring the occurrence of thioflavin-T-positive insulin amyloid aggregation intermediates
por: Ziaunys, Mantas, et al.
Publicado: (2021)

Exogenous NADPH ameliorates myocardial ischemia–reperfusion injury in rats through activating AMPK/mTOR pathway
por: Zhu, Jiang, et al.
Publicado: (2019)

Equivalent intraperitoneal doses of ibuprofen supplemented in drinking water or in diet: a behavioral and biochemical assay using antinociceptive and thromboxane inhibitory dose–response curves in mice
por: Salama, Raghda A.M., et al.
Publicado: (2016)

Driver versus navigator causation in biology: the case of insulin and fasting glucose
por: Diwekar-Joshi, Manawa, et al.
Publicado: (2020)

Overexpression of LINC00551 promotes autophagy-dependent ferroptosis of lung adenocarcinoma via upregulating DDIT4 by sponging miR-4328
por: Peng, Xiong, et al.
Publicado: (2022)

The insulin receptor cellular IRES confers resistance to eIF4A inhibition
por: Olson, Calla M, et al.
Publicado: (2013)

miR-455-3p ameliorates pancreatic acinar cell injury by targeting Slc2a1
por: Zhan, Yinchu, et al.
Publicado: (2023)

Pramipexole has a neuroprotective effect in spinal cord injury and upregulates D2 receptor expression in the injured spinal cord tissue in rats
por: Liu, Xuchen, et al.
Publicado: (2023)

Lp-PLA2 silencing ameliorates inflammation and autophagy in nonalcoholic steatohepatitis through inhibiting the JAK2/STAT3 pathway
por: Yao, Jinmei, et al.
Publicado: (2023)

The role of autophagy in high-fat diet-induced insulin resistance of adipose tissues in mice
por: Budi, Yovita Permata, et al.
Publicado: (2022)

Construction of a ceRNA network of regulated ferroptosis in doxorubicin-induced myocardial injury
por: Ye, Hongwei, et al.
Publicado: (2023)

miR-214 ameliorates sepsis-induced acute kidney injury via PTEN/AKT/mTOR-regulated autophagy
por: Sang, Zhenzhen, et al.
Publicado: (2021)

Transplantation of adipose-derived stem cells overexpressing inducible nitric oxide synthase ameliorates diabetes mellitus-induced erectile dysfunction in rats
por: Zhang, Yan, et al.
Publicado: (2019)

Taxifolin protects rat against myocardial ischemia/reperfusion injury by modulating the mitochondrial apoptosis pathway
por: Tang, Zhenqiu, et al.
Publicado: (2019)

In vivo evaluation of the protective effects of arjunolic acid against lipopolysaccharide-induced septic myocardial injury
por: Elsawy, Hany, et al.
Publicado: (2022)

The Role of Mammalian Target of Rapamycin (mTOR) in Insulin Signaling
por: Yoon, Mee-Sup
Publicado: (2017)

Relationship between iron status markers and insulin resistance: an exploratory study in subjects with excess body weight
por: Vaquero, M. Pilar, et al.
Publicado: (2020)

MiR-190 ameliorates glucotoxicity-induced dysfunction and apoptosis of pancreatic β-cells by inhibiting NOX2-mediated reactive oxygen species production
por: Lu, Huinan, et al.
Publicado: (2022)

Ferroptotic cardiomyocyte-derived exosomes promote cardiac macrophage M1 polarization during myocardial infarction
por: Sun, Shengjia, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0u6047m6fd9ml8stgv9p73g2pn