The Valproate Mediates Radio-Bidirectional Regulation Through RFWD3-Dependent Ubiquitination on Rad51

Ionizing radiation (IR) can induce DNA double-strand breaks (DSBs) in tumor cells during radiotherapy (RT), but the efficiency of RT is limited because of the toxicity to normal cells. Locating an adjuvant treatment to alleviate damage in normal cells while sensitizing tumor cells to IR has attracte...

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Detalles Bibliográficos
Autores principales: Liu, Guochao, Lim, David, Cai, Zuchao, Ding, Wenwen, Tian, Zhujun, Dong, Chao, Zhang, Fengmei, Guo, Gongshe, Wang, Xiaowei, Zhou, Pingkun, Feng, Zhihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8029989/
https://www.ncbi.nlm.nih.gov/pubmed/33842359
http://dx.doi.org/10.3389/fonc.2021.646256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8029989/
https://www.ncbi.nlm.nih.gov/pubmed/33842359
http://dx.doi.org/10.3389/fonc.2021.646256

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