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Digital thermal monitoring techniques to assess vascular reactivity following finger and brachial occlusions

Digital thermal monitoring (DTM) is an alternative, noninvasive, methodology to evaluate endothelial function using temperature change on finger as a surrogate measure of the magnitude of vascular reactivity index (VRI). A most recent modification to the technique includes the application of occlusi...

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Autores principales: Heath, Melanie, Gourley, Drew, Naghavi, Morteza, Klies, Stanley, Tanaka, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8030097/
http://dx.doi.org/10.1111/jch.14115
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author Heath, Melanie
Gourley, Drew
Naghavi, Morteza
Klies, Stanley
Tanaka, Hirofumi
author_facet Heath, Melanie
Gourley, Drew
Naghavi, Morteza
Klies, Stanley
Tanaka, Hirofumi
author_sort Heath, Melanie
collection PubMed
description Digital thermal monitoring (DTM) is an alternative, noninvasive, methodology to evaluate endothelial function using temperature change on finger as a surrogate measure of the magnitude of vascular reactivity index (VRI). A most recent modification to the technique includes the application of occlusion cuff at the base of a finger. We evaluated the validity of DTM compared with the standard flow‐mediated dilation (FMD) protocol. Thirty‐eight (22 males; 38 ± 15 years) participants were studied. Occlusion cuff was placed over the right antecubital fossa or at the base of the right index finger. Temperature monitors were placed on bilateral index fingers to assess change in temperature throughout 5‐min occlusion and recovery phases. VRI values obtained with the finger occlusion (1.58 ± 0.29 AU) were not significantly different from VRI measured with the brachial artery occlusion (1.55 ± 0.26 AU; p = .47), and the agreement of VRI values was confirmed in the Bland‐Altman plot with a mean difference of −0.03 ± 0.34 (95% confidence interval: −0.15 to 0.09). Shear rate(AUCI) was significantly correlated with VRI obtained from brachial occlusion (r = .34) and finger occlusion VRI (r = .54; all p < .05). Moreover, brachial FMD was significantly correlated with brachial occlusion VRI (r = .69; p < .05) and finger occlusion VRI (r = .53; p < .05). Therefore, finger‐based VRI may be a valid and novel alternative measure of endothelial function that is more suitable than the standard FMD or hyperemic shear rate for the assessment of endothelial function in the routine clinical setting.
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spelling pubmed-80300972021-12-16 Digital thermal monitoring techniques to assess vascular reactivity following finger and brachial occlusions Heath, Melanie Gourley, Drew Naghavi, Morteza Klies, Stanley Tanaka, Hirofumi J Clin Hypertens (Greenwich) Vascular Reactivity Digital thermal monitoring (DTM) is an alternative, noninvasive, methodology to evaluate endothelial function using temperature change on finger as a surrogate measure of the magnitude of vascular reactivity index (VRI). A most recent modification to the technique includes the application of occlusion cuff at the base of a finger. We evaluated the validity of DTM compared with the standard flow‐mediated dilation (FMD) protocol. Thirty‐eight (22 males; 38 ± 15 years) participants were studied. Occlusion cuff was placed over the right antecubital fossa or at the base of the right index finger. Temperature monitors were placed on bilateral index fingers to assess change in temperature throughout 5‐min occlusion and recovery phases. VRI values obtained with the finger occlusion (1.58 ± 0.29 AU) were not significantly different from VRI measured with the brachial artery occlusion (1.55 ± 0.26 AU; p = .47), and the agreement of VRI values was confirmed in the Bland‐Altman plot with a mean difference of −0.03 ± 0.34 (95% confidence interval: −0.15 to 0.09). Shear rate(AUCI) was significantly correlated with VRI obtained from brachial occlusion (r = .34) and finger occlusion VRI (r = .54; all p < .05). Moreover, brachial FMD was significantly correlated with brachial occlusion VRI (r = .69; p < .05) and finger occlusion VRI (r = .53; p < .05). Therefore, finger‐based VRI may be a valid and novel alternative measure of endothelial function that is more suitable than the standard FMD or hyperemic shear rate for the assessment of endothelial function in the routine clinical setting. John Wiley and Sons Inc. 2020-12-07 /pmc/articles/PMC8030097/ http://dx.doi.org/10.1111/jch.14115 Text en © 2020 The Authors. The Journal of Clinical Hypertension published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Vascular Reactivity
Heath, Melanie
Gourley, Drew
Naghavi, Morteza
Klies, Stanley
Tanaka, Hirofumi
Digital thermal monitoring techniques to assess vascular reactivity following finger and brachial occlusions
title Digital thermal monitoring techniques to assess vascular reactivity following finger and brachial occlusions
title_full Digital thermal monitoring techniques to assess vascular reactivity following finger and brachial occlusions
title_fullStr Digital thermal monitoring techniques to assess vascular reactivity following finger and brachial occlusions
title_full_unstemmed Digital thermal monitoring techniques to assess vascular reactivity following finger and brachial occlusions
title_short Digital thermal monitoring techniques to assess vascular reactivity following finger and brachial occlusions
title_sort digital thermal monitoring techniques to assess vascular reactivity following finger and brachial occlusions
topic Vascular Reactivity
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8030097/
http://dx.doi.org/10.1111/jch.14115
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