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Quantification of von Willebrand factor and ADAMTS-13 after traumatic injury: a pilot study
BACKGROUND: Von Willebrand factor (VWF) is an acute phase reactant synthesized in the megakaryocytes and endothelial cells. VWF forms ultra-large multimers (ULVWF) which are cleaved by the metalloprotease ADAMTS-13, preventing spontaneous VWF–platelet interaction. After trauma, ULVWF is released int...
Autores principales: | MacArthur, Taleen A, Goswami, Julie, Moon Tasson, Laurie, Tischer, Alexander, Bailey, Kent R, Spears, Grant M, Dong, Jing-Fei, Auton, Matthew, Kozar, Rosemary, Park, Myung S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8030476/ https://www.ncbi.nlm.nih.gov/pubmed/33912688 http://dx.doi.org/10.1136/tsaco-2021-000703 |
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