Case Report: Coinheritance of Germline Mutations in APC and BRCA1 in Colorectal Cancer

Deleterious mutations in APC gene cause the autosomal dominant familial adenomatous polyposis (FAP) which is typically characterized by the occurrence of hundreds to thousands of colorectal adenomas that eventually lead to colorectal cancers (CRCs). BRCA1/2 are the two major susceptibility genes for...

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Detalles Bibliográficos
Autores principales: Huang, Wei, Bian, Jin, Qian, Xiaoping, Shao, Lin, Li, Haiyan, Zhang, Lu, Wang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8030582/
https://www.ncbi.nlm.nih.gov/pubmed/33842374
http://dx.doi.org/10.3389/fonc.2021.658389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8030582/
https://www.ncbi.nlm.nih.gov/pubmed/33842374
http://dx.doi.org/10.3389/fonc.2021.658389

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