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PLD3 is a neuronal lysosomal phospholipase D associated with β-amyloid plaques and cognitive function in Alzheimer’s disease

Phospholipase D3 (PLD3) is a protein of unclear function that structurally resembles other members of the phospholipase D superfamily. A coding variant in this gene confers increased risk for the development of Alzheimer’s disease (AD), although the magnitude of this effect has been controversial. B...

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Detalles Bibliográficos
Autores principales: Nackenoff, Alex G., Hohman, Timothy J., Neuner, Sarah M., Akers, Carolyn S., Weitzel, Nicole C., Shostak, Alena, Ferguson, Shawn M., Mobley, Bret, Bennett, David A., Schneider, Julie A., Jefferson, Angela L., Kaczorowski, Catherine C., Schrag, Matthew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8031396/
https://www.ncbi.nlm.nih.gov/pubmed/33830999
http://dx.doi.org/10.1371/journal.pgen.1009406