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Flipping the switch on the hub cell: Islet desynchronization through cell silencing
Pancreatic β cells, responsible for secreting insulin into the bloodstream and maintaining glucose homeostasis, are organized in the islets of Langerhans as clusters of electrically coupled cells. Gap junctions, connecting neighboring cells, coordinate the behavior of the islet, leading to the synch...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8031451/ https://www.ncbi.nlm.nih.gov/pubmed/33831017 http://dx.doi.org/10.1371/journal.pone.0248974 |