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How does Sec63 affect the conformation of Sec61 in yeast?

The Sec complex catalyzes the translocation of proteins of the secretory pathway into the endoplasmic reticulum and the integration of membrane proteins into the endoplasmic reticulum membrane. Some substrate peptides require the presence and involvement of accessory proteins such as Sec63. Recently...

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Detalles Bibliográficos
Autores principales: Bhadra, Pratiti, Yadhanapudi, Lalitha, Römisch, Karin, Helms, Volkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8031780/
https://www.ncbi.nlm.nih.gov/pubmed/33780447
http://dx.doi.org/10.1371/journal.pcbi.1008855