Neurodevelopment in the third year of life in children with antenatal ZIKV-exposure

We report cognitive, language and motor neurodevelopment, assessed by the Bayley-III test, in 31 non-microcephalic children at age 3 with PCR-confirmed maternal Zika virus exposure (Rio de Janeiro, 2015–2016). Most children had average neurodevelopmental scores, however, 8 children (26%) presented d...

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Detalles Bibliográficos
Autores principales: Aizawa, Carolina Yuri Panvequio, Caron, Deyse Mayara Rodrigues, de Souza, Carolina Barbosa, Kozima, Paula Fernanda Augusto, Damasceno, Luana, Einspieler, Christa, Marschik, Peter B., Brasil, Patrícia, Schmitt, Ana Carolina Basso, Nielsen-Saines, Karin, Hasue, Renata Hydee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade de Saúde Pública da Universidade de São Paulo 2021
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032323/
https://www.ncbi.nlm.nih.gov/pubmed/33909869
http://dx.doi.org/10.11606/s1518-8787.2021055002798
Descripción
Sumario:We report cognitive, language and motor neurodevelopment, assessed by the Bayley-III test, in 31 non-microcephalic children at age 3 with PCR-confirmed maternal Zika virus exposure (Rio de Janeiro, 2015–2016). Most children had average neurodevelopmental scores, however, 8 children (26%) presented delay in some domain. Language was the most affected: 7 children (22.6%) had a delay in this domain (2 presenting severe delay). Moderate delay was detected in the cognitive (3.2%) and motor (10%) domains. Maternal illness in the third trimester of pregnancy and later gestational age at birth were associated with higher Bayley-III scores. Zika-exposed children require long-term follow-up until school age.

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