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Increased Gene Copy Number of DEFA1A3 Is Associated With the Severity of Ulcerative Colitis

DEFA1A3 encodes human neutrophil peptides (HNPs) 1–3 and has multiple copy number variations (CNVs). HNPs are associated with innate immunity. Ulcerative colitis (UC), a chronic inflammatory gastrointestinal disorder, is a life-threatening condition, and predictive markers of UC severity are needed....

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Detalles Bibliográficos
Autores principales:	Kanmura, Shuji, Morinaga, Yuko, Tanaka, Akihito, Komaki, Yuga, Iwaya, Hiromichi, Kumagai, Kotaro, Mawatari, Seiichi, Sasaki, Fumisato, Tanoue, Shiroh, Hashimoto, Shinichi, Sameshima, Yoichi, Ono, Yohei, Ohi, Hidehisa, Ido, Akio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032364/ https://www.ncbi.nlm.nih.gov/pubmed/33825720 http://dx.doi.org/10.14309/ctg.0000000000000331

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