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Association of Early β-Amyloid Accumulation and Neuroinflammation Measured With [(11)C]PBR28 in Elderly Individuals Without Dementia

OBJECTIVE: To examine whether early β–amyloid (Aβ) accumulation and metabolic risk factors are associated with neuroinflammation in elderly individuals without dementia. METHODS: We examined 54 volunteers (mean age 70.0 years, 56% women, 51% APOE ɛ4 carriers) with the translocator protein (TSPO) tra...

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Detalles Bibliográficos
Autores principales:	Toppala, Sini, Ekblad, Laura L., Tuisku, Jouni, Helin, Semi, Johansson, Jarkko J., Laine, Hanna, Löyttyniemi, Eliisa, Marjamäki, Päivi, Blennow, Kaj, Zetterberg, Henrik, Jula, Antti, Viitanen, Matti, Rinne, Juha O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032368/ https://www.ncbi.nlm.nih.gov/pubmed/33514647 http://dx.doi.org/10.1212/WNL.0000000000011612

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