Aurora-A kinase oncogenic signaling mediates TGF-β-induced triple-negative breast cancer plasticity and chemoresistance

Triple-negative breast cancer (TNBCs) account for 15–20% of all breast cancers and represent the most aggressive subtype of this malignancy. Early tumor relapse and progression are linked to the enrichment of a sub-fraction of cancer cells, termed breast tumor-initiating cells (BTICs), that undergo...

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Detalles Bibliográficos
Autores principales: Jalalirad, Mohammad, Haddad, Tufia C., Salisbury, Jeffrey L., Radisky, Derek, Zhang, Minzhi, Schroeder, Mark, Tuma, Ann, Leof, Eduard, Carter, Jodi M., Degnim, Amy C., Boughey, Judy C., Sarkaria, Jann, Yu, Jia, Wang, Liewei, Liu, Minetta C., Zammataro, Luca, Malatino, Lorenzo, Galanis, Evanthia, Ingle, James N., Goetz, Matthew P., D’Assoro, Antonino B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032554/
https://www.ncbi.nlm.nih.gov/pubmed/33674749
http://dx.doi.org/10.1038/s41388-021-01711-x

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