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Serum 4β-hydroxycholesterol increases during fluconazole treatment

PURPOSE: The antifungal drugs ketoconazole and itraconazole reduce serum concentrations of 4β-hydroxycholesterol, which is a validated marker for hepatic cytochrome P450 (CYP) 3A4 activity. We tested the effect of another antifungal triazole agent, fluconazole, on serum concentrations of different s...

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Detalles Bibliográficos
Autores principales:	Lütjohann, Dieter, Stellaard, Frans, Kerksiek, Anja, Lötsch, Jörn, Oertel, Bruno G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Clinical Trial
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032583/ https://www.ncbi.nlm.nih.gov/pubmed/33201347 http://dx.doi.org/10.1007/s00228-020-03041-5

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