Normal fat mass cannot be reliably estimated in typical pharmacokinetic studies

PURPOSE: An influential covariate for pharmacokinetics is (body) size. Recently, the method of estimation of normal fat mass (NFM) has been advocated. Here, the relative contribution of fat mass, estimated as a fraction fat (Ffat), is used to explain differences in pharmacokinetic parameters. This c...

Descripción completa

Detalles Bibliográficos
Autores principales: Wasmann, Roeland E., Svensson, Elin M., Schalkwijk, Stein J., Brüggemann, Roger J., ter Heine, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Pharmacokinetics and Disposition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032617/
https://www.ncbi.nlm.nih.gov/pubmed/33205282
http://dx.doi.org/10.1007/s00228-020-03042-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032617/
https://www.ncbi.nlm.nih.gov/pubmed/33205282
http://dx.doi.org/10.1007/s00228-020-03042-4

Ejemplares similares