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Physiological and pharmacological stimulation for in vitro maturation of substrate metabolism in human induced pluripotent stem cell-derived cardiomyocytes

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) enable human cardiac cells to be studied in vitro, although they use glucose as their primary metabolic substrate and do not recapitulate the properties of adult cardiomyocytes. Here, we have explored the interplay between matura...

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Detalles Bibliográficos
Autores principales:	Lopez, Colleen A., Al-Siddiqi, Heba Hussain A. A., Purnama, Ujang, Iftekhar, Sonia, Bruyneel, Arne A. N., Kerr, Matthew, Nazir, Rabia, da Luz Sousa Fialho, Maria, Malandraki-Miller, Sophia, Alonaizan, Rita, Kermani, Fatemeh, Heather, Lisa C., Czernuszka, Jan, Carr, Carolyn A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032667/ https://www.ncbi.nlm.nih.gov/pubmed/33833285 http://dx.doi.org/10.1038/s41598-021-87186-y

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