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Identification of critical amino acid residues in the regulatory N-terminal domain of PMEL
The pigment cell-specific protein PMEL forms a functional amyloid matrix in melanosomes onto which the pigment melanin is deposited. The amyloid core consists of a short proteolytic fragment, which we have termed the core-amyloid fragment (CAF) and perhaps additional parts of the protein, such as th...
Autores principales: | Mitchell, Susan M., Graham, Morven, Liu, Xinran, Leonhardt, Ralf M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032716/ https://www.ncbi.nlm.nih.gov/pubmed/33833328 http://dx.doi.org/10.1038/s41598-021-87259-y |
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