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Genetic variants of programmed cell death 1 are associated with HBV infection and liver disease progression
The inhibitory effects of programmed cell death 1/programmed cell death ligand 1 (PD-1/PD-L1) modulates T-cell depletion. T-cell depletion is one of the key mechanisms of hepatitis B virus (HBV) persistence, in particular liver disease progression and the development of hepatocellular carcinoma (HCC...
Autores principales: | Hoan, Nghiem Xuan, Huyen, Pham Thi Minh, Binh, Mai Thanh, Trung, Ngo Tat, Giang, Dao Phuong, Linh, Bui Thuy, Dung, Dang Thi Ngoc, Pallerla, Srinivas Reddy, Kremsner, Peter G., Velavan, Thirumalaisamy P., Bang, Mai Hong, Song, Le Huu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032722/ https://www.ncbi.nlm.nih.gov/pubmed/33833369 http://dx.doi.org/10.1038/s41598-021-87537-9 |
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