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Symbiotic polyamine metabolism regulates epithelial proliferation and macrophage differentiation in the colon
Intestinal microbiota-derived metabolites have biological importance for the host. Polyamines, such as putrescine and spermidine, are produced by the intestinal microbiota and regulate multiple biological processes. Increased colonic luminal polyamines promote longevity in mice. However, no direct e...
Autores principales: | Nakamura, Atsuo, Kurihara, Shin, Takahashi, Daisuke, Ohashi, Wakana, Nakamura, Yutaka, Kimura, Shunsuke, Onuki, Masayoshi, Kume, Aiko, Sasazawa, Yukiko, Furusawa, Yukihiro, Obata, Yuuki, Fukuda, Shinji, Saiki, Shinji, Matsumoto, Mitsuharu, Hase, Koji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032791/ https://www.ncbi.nlm.nih.gov/pubmed/33833232 http://dx.doi.org/10.1038/s41467-021-22212-1 |
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