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The Dose-Dependent Pleiotropic Effects of the UBB(+1) Ubiquitin Mutant

The proteolytic machinery activity diminishes with age, leading to abnormal accumulation of aberrant proteins; furthermore, a decline in protein degradation capacity is associated with multiple age-related proteinopathies. Cellular proteostasis can be maintained via the removal of ubiquitin (Ub)-tag...

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Detalles Bibliográficos
Autores principales:	Banasiak, Katarzyna, Szulc, Natalia A., Pokrzywa, Wojciech
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032880/ https://www.ncbi.nlm.nih.gov/pubmed/33842548 http://dx.doi.org/10.3389/fmolb.2021.650730

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