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Inflammatory Foreign Body Response Induced by Neuro-Implants in Rat Cortices Depleted of Resident Microglia by a CSF1R Inhibitor and Its Implications

Inflammatory encapsulation of implanted cortical-neuro-probes [the foreign body response (FBR)] severely limits their use in basic brain research and in clinical applications. A better understanding of the inflammatory FBR is needed to effectively mitigate these critical limitations. Combining the u...

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Detalles Bibliográficos
Autores principales: Sharon, Aviv, Jankowski, Maciej M., Shmoel, Nava, Erez, Hadas, Spira, Micha E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8032961/
https://www.ncbi.nlm.nih.gov/pubmed/33841088
http://dx.doi.org/10.3389/fnins.2021.646914