Hepatitis B virus resistance to tenofovir: fact or fiction? A systematic literature review and structural analysis of drug resistance mechanisms

Background: Tenofovir (TFV) is a widely used treatment for chronic hepatitis B virus (HBV) infection. There is a high genetic barrier to the selection of TFV resistance-associated mutations (RAMs), but the distribution and clinical significance of TFV RAMs are not well understood. We here present as...

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Detalles Bibliográficos
Autores principales: Mokaya, Jolynne, McNaughton, Anna L., Bester, Phillip A, Goedhals, Dominique, Barnes, Eleanor, Marsden, Brian D, Matthews, Philippa C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2020
Materias:
Systematic Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033640/
https://www.ncbi.nlm.nih.gov/pubmed/33869791
http://dx.doi.org/10.12688/wellcomeopenres.15992.1

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