Long-read sequencing and de novo genome assemblies reveal complex chromosome end structures caused by telomere dysfunction at the single nucleotide level

Karyotype change and subsequent evolution is triggered by chromosome fusion and rearrangement events, which often occur when telomeres become dysfunctional. Telomeres protect linear chromosome ends from DNA damage responses (DDRs), and telomere dysfunction may result in genome instability. However,...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Eunkyeong, Kim, Jun, Kim, Chuna, Lee, Junho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034613/
https://www.ncbi.nlm.nih.gov/pubmed/33693840
http://dx.doi.org/10.1093/nar/gkab141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034613/
https://www.ncbi.nlm.nih.gov/pubmed/33693840
http://dx.doi.org/10.1093/nar/gkab141

Ejemplares similares