A novel RNA pol II CTD interaction site on the mRNA capping enzyme is essential for its allosteric activation

Recruitment of the mRNA capping enzyme (CE/RNGTT) to the site of transcription is essential for the formation of the 5′ mRNA cap, which in turn ensures efficient transcription, splicing, polyadenylation, nuclear export and translation of mRNA in eukaryotic cells. The CE GTase is recruited and activa...

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Detalles Bibliográficos
Autores principales: Bage, Marcus G, Almohammed, Rajaei, Cowling, Victoria H, Pisliakov, Andrei V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034621/
https://www.ncbi.nlm.nih.gov/pubmed/33684220
http://dx.doi.org/10.1093/nar/gkab130

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